Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy of its genome. The findings, published in Nature Communications, reveal where DNA first begins to "unzip" inside living cells and identify a molecular gate that helps prepare DNA for copying.

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy of its genome. The findings, published in Nature Communications, reveal where DNA first begins to “unzip” inside living cells and identify a molecular gate that helps prepare DNA for copying.

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