A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates receptor dynamics and activation of the human adenosine A2A receptor (A2AR), a major G protein-coupled receptor (GPCR) drug target. The study is published in the Proceedings of the National Academy of Sciences.

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates receptor dynamics and activation of the human adenosine A2A receptor (A2AR), a major G protein-coupled receptor (GPCR) drug target. The study is published in the Proceedings of the National Academy of Sciences.

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