Antibiotics are medical marvels that have transformed once deadly bacterial infections into manageable conditions. But with a rise in antibiotic resistance that renders existing treatments ineffective, new agents are urgently needed. Scientists at Caltech and Princeton University have now shed fresh light on why antibiotics that work well in laboratory tests often fail against real infections in humans.

Antibiotics are medical marvels that have transformed once deadly bacterial infections into manageable conditions. But with a rise in antibiotic resistance that renders existing treatments ineffective, new agents are urgently needed. Scientists at Caltech and Princeton University have now shed fresh light on why antibiotics that work well in laboratory tests often fail against real infections in humans.

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